Abstract: Instruments and equipment in colleges and universities, as the main hardware resources of the laboratory, play an important role in talent cultivation and disciplinary development. In view of problems such as non-standard management, low utilization rates, untimely maintenance and repair, and discrepancies between accounts and actual equipment in colleges and universities, the study proposes that by improving mechanism construction, enhancing equipment budget management, and building intelligent platforms, an intelligent management system for instruments and equipment in colleges and universities was established to improve the performance of instruments and equipment management and assist in the construction of "Double First Class" initative and their leapfrog development.