Determination of Nicotine in Tobacco Concrete by Gas Chromatography

A gas chromatography-flame ionization (GC-FID) method has been developed for the determination of nicotine in the tobacco concrete using 2-methylquinoline as the internal standards, five tobacco concrete samples were determined. The results showed that the limit of detection and limit of quantitation were 0.27 mg/g and 0.89 mg/g, respectively. The recoveries were 95.00%~98.58%. The contents of nicotine in the samples ranged from 19.66~54.97 mg/g. The method is easy, sensitive and accurate, and is suitable for the determination of nicotine in the tobacco concrete.