Bio-Mass Spectrometry

Mass spectrometry has become an important analytical tool in biological and biochemical research. Its speed, accuracy and sensitivity are unmatched by conventional analytical techniques. The matrix assisted laser desorption ionization-time of flight MS(MALDI-TOF-MS) and electrospray ionization MS can efficiently solve many questions in proteomics. This review concerns principles and methods of MALDI-MS and ESI-MS. The some applications of mass spectrometry in protein and peptides analysis are shown also.