Determination of Lovastatin and Lovastatin Acid by High Performance Liquid Chromatography
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Graphical Abstract
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Abstract
An improved reverse phase HPLC method has been established to determine lovastatin and lovastatin acid. The C4 column and the UV detector were applied, and methanol-water(80:20) was used as the mobile phase. The experimental results show that the improved chromatographic conditions can be used to analyze the lovastatin and lovastatin acid effectively and economically.
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