Determination of Residual Organic Solvents in TOPAMAX by GC

Four residual organic solvents (ethanol、acetone、THF、toluene) in TOPAMAX were determined by packed chromatographic column of FID-GC via external correlation method. The analytical validation for each of residual solvents was performed with respect to the following validation characteristics: linearity, accuracy, precision, specificity, detection limit.