The Study of the Voltammetric Behaviour of 7-methylguanosineon Glassy Carbon Electrode

The electrochemical response of 7-methylguanosine in pH 1.98 B-R buffer was investigated by cyclic voltammetry (CV), linear sweep voltammetry (LSV) and differential pulse voltammetry (DPV) method. The differential pules voltammetry exhibited an oxidation current peak of 7-methylguanosine at the potential of +1.036 V (vs. SCE). The peak current is linearly increased with the concentration of 7-methylguanosine in the range of 5.0×10^-5~2.0×10^-6 mol/L. The detection limit is 4.1×10^-7 mol/L. The possible mechanism for the irreversible reaction was assumed to be the oxidation lossing of one proton and two electrons.