Study on Thyroglobulin Bovine by Matrix-Assisted LaserDesorption Ionization Mass Spectrometry

The purity and the relativity molecular weight of thyroglobulin bovine were characterized by matrix-assisted laser desorption ionization mass spectrometry (MALDI-TOF-MS). Three kinds of matrix were compared and the results showed that sinapic acid（SA）was the effective matrix. Some advantages such as high sensitivity, good reproducibility and direct information make this analytical technique better than conventional method.